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Search Results for " ap 10 "

8

Compounds

Cat No. Product Name Synonyms Targets
TQ0185 14-Deoxy-11,12-didehydroandrographolide AP10,14-dehydro Andrographolide NF-κB
14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.
T23027 MRT-10 Hedgehog/Smoothened
MRT-10 is a Smoothened (Smo) receptor antagonist.
T8425 Linoleoyl Ethanolamide TRP/TRPV Channel
Linoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation and AP-1 dependent transcription in CB-receptor in an independent manner.
T4567 Sulfaphenazole Plisulfan,Raziosulfa,Depocid,Depotsulfonamide P450 , Antibacterial
Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1...
T25573 Ketomethylenebestatin
Ketomethylenebestatin is a carba-analog of bestatin,the aminopeptidase (AP) inhibitor. Ketomethylenebestatin is 10 fold less effective as an inhibitor of aminopeptidases than bestatin.
T83856 AP-1
AP-1, a miniaturized proteolysis-targeting chimera (PROTAC) incorporating an anaplastic lymphoma kinase (ALK) ligand connected to (±)-thalidomide via an ultrashort linker, effectively degrades ALK fusion proteins such as...
TN5639 Rocaglaol Ferrugin,Aglaiastatin A
Rocaglaol is a potent anticancer drug that induces apoptosis of LNCaP cells through the mitochondrial pathway and its G2/M-phase cell cycle arrest is associated with the down-regulation of Cdc25C and the dephosphorylatio...
T70063 GYKI 52466 HCl
GYKI 52466 is an allosteric AMPA receptor antagonist. It selectively inhibits AMPA-induced inward currents (IC50 = 7.5 µM) over NMDA- or GABA-induced inward currents in primary rat hippocampal neurons at 50 µM but also i...
TargetMol